Thistle Ridge Doodles
Premier Breeder of Goldendoodles, Australian Labradoodles and the beautiful cross between the two; Double Doodles
Disease Testing Each and Every Parent Line Receives Before Being Allowed to Breed.
Golden Retriever Lines Receive the Following Testing
OFA Hips, Elbows and Patella's
OFA Cardiac
Baseline Thyroid
Degenerative Myelopathy
Dystrophic Epidermolysis Bullosa
Ichthyosis
Muscular Dystrophy
Osteogenesis Imperfecta
Progressive Retinal Atrophy 1
Progressive Retinal Atrophy 2
Preogressive Retinal Atrophy, Progressive Rod-Cone Degeneration
Sensory Ataxic Neuropathy
Poodle Lines Receive the Following Testing
OFA Hips, Elbows and Patella's
OFA Cardiac
Baseline Thyroid
Degenerative Myelopathy
GM2 Gangliosidosis
Neonatal Encephalopathy with Seizures
Preogressive Retinal Atrophy, Progressive Rod-Cone Degeneration
Von Willbrand Disease 1
IC Locus (Improper Coat/Furnishings)
Goldendoodle Lines Receive the Following Testing which is the Combination of the Golden Retriever and Poodle Testing.
OFA Hips, Elbows and Patella's
OFA Cardiac
Baseline Thyroid
Degenerative Myelopathy
Dystrophic Epidermolysis Bullosa
Ichthyosis
Muscular Dystrophy
Osteogenesis Imperfecta
Progressive Retinal Atrophy 1
Progressive Retinal Atrophy 2
Preogressive Retinal Atrophy, Progressive Rod-Cone Degeneration
Sensory Ataxic Neuropathy
GM2 Gangliosidosis
Neonatal Encephalopathy with Seizures
Preogressive Retinal Atrophy, Progressive Rod-Cone Degeneration
Von Willbrand Disease 1
IC Locus (Improper Coat/Furnishings)
All Labradoodle Parents Receive the Following Testing
OFA Hips, Elbows and Patella's
OFA Cardiac
Baseline Thyroid
Centronuclear Myopathy
Cystinuria
Degenerative Myelopathy
Exercise-Induced Collapse
Familial Nephropathy
Glycogen Storage Disease VII, PFK Deficiency
Hereditary Nasal Parakeratosis
Myotubular Myopathy 1
Narcolepsy
Neonatal Encephalopathy with Seizures
Progessive Retinal Atrophy, Cone-Rod Dystrophy 4
Progressive Retinal Atrophy, Progressive Rod-Cone Degeneration
Retinal Dysplasia/Oculoskeletal Dysplasia 1
Skeletal Dysplasia 2
Von Willebrand Disease 1
IC Locus (Improper Coat/Furnishings)
ALL Double Doodle lines (combination of a generation of Golden Retriever, Labrador Retriever and Poodle)
OFA Hips/ Elbows - http://www.ofa.org/hd_grades.html
Thyroid - http://www.ofa.org/thy_proc.html
VwD - https://www.vetgen.com/canine-vwd.html
DM - https://www.vetgen.com/canine-dm.html
Cardiac - http://www.ofa.org/cardiac_about.html
Patella - http://www.ofa.org/pl_overview.html
IC Locus (Improper Coat Furnishings)
Test Names:
furnishings, improper coat, Wh locus, wire hair trait, wirehaired trait
furnishings, improper coat, Wh locus, wire hair trait, wirehaired traitAffected Genes:RSPO2
RSPO2Inheritance:Autosomal Recessive (Improper Coat); Autosomal Dominant (Furnishings)
Autosomal Recessive (Improper Coat); Autosomal Dominant (Furnishings)Mutation:Insertion
InsertionBreed(s):All Breeds
All BreedsTesting Summary
The IC Locus (Improper coat/Furnishings) trait test reliably determines if a dog has one of the following genotypes at the IC locus:
F/F
This dog does not carry the Mutation for improper coat and will therefore have furnishings (proper coat). However, the overall coat type of this dog is dependent on the combination of this dog's genotypes at the L, Cu, and IC loci. This dog will pass F (furnishings, proper coat) on to 100% of its offspring.
Interpretation: Furnishings
F/IC
This dog carries one copy of the mutation for improper coat (IC) and one copy of F and will therefore have furnishings (proper coat). However, the overall coat type of this dog is dependent on the combination of this dog's genotypes at the L, Cu, and IC loci. This dog will pass IC (improper coat) on to 50% of its offspring and F (furnishings, proper coat) on to 50% of its offspring. Therefore, this dog can produce puppies with improper coat if bred with a dog that carries one copy (F/IC) or two copies (IC/IC) of the mutation for improper coat.
Interpretation: Furnishings (Improper coat Carrier)
IC/IC
This dog carries two copies of IC and will therefore have no furnishings (improper coat). However, the overall coat type of this dog is dependent on the combination of this dog's genotypes at the L, Cu, and IC loci. This dog will pass IC (improper coat) on to 100% of its offspring and can produce puppies with improper coat if bred with a dog that carries one copy (F/IC) or two copies (IC/IC) of the mutation for improper coat.
Interpretation: No Furnishings, improper coat
Detailed Summary
The improper coat/furnishings (IC) Locus determines if a dog will have longer hair around the muzzle and eyebrows (facial furnishings) or a lack of furnishings (called improper coat in breeds for which facial furnishings are standard). A DNA variant in the RSPO2 gene, which functions in hair follicle development, results in the production of furnishings in multiple breeds and is found in all wire-haired dogs.
Testing Tips
Genetic testing of the IC Locus for the RSPO2 gene variant will reliably determine whether a dog has furnishings or improper coat and whether or not a dog has furnishings and is a Carrier of improper coat. Facial furnishings are inherited in an Autosomal Dominant fashion, meaning only one copy of the RSPO2 variant is required to produce furnishings. Improper coat is, therefore, recessive to furnishings, meaning two copies of IC are required to inherit an improper coat and dogs with furnishings can be carriers of improper coat that can be passed on to their offspring.
Health testing is very important to us and rightly so. We as your selected breeder want to give you not only "The best dog you have ever owned" but one of the healthiest; living a very long and happy life. By doing our due diligence with our care and genetic testing and by only breeding parents that lineage has passed our stringent expectations with the highest of results we hope to produce a healthier line of puppies.
